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Alternatives to Viagra
By: Candice E. Dobbins, Fri Jan 15th, 2010
Viagra, the miracle pill that allowed thousands of men with erectile dysfunction enjoy a healthy sex life, has to face tough competition.
Viagra (Sildenafil trade mark) became embodied in a miracle blue pill for all men and women suffering in silence the hard state of sexual impotence. This medicine opened the doors to a new way of approaching the treatment of erectile dysfunction. From here, many pharmaceutical companies were launched to search for new drugs that improve the efficiency of the famous Viagra and reduced side effects, from here you can find viagra online in an easier way in the market for consumption mass.
The result: Cialis, Uprima, Ixense and Levitra. Some are already approved for marketing and other in-process. Medicines immediate effect, longer duration and with fewer side effects. A wider range of possibilities for your partner to choose.
¿Cómo funcionan?
The erection occurs when blood flow is diverted to genital body cavernosum (spongy cylinders located in the center of the member). A process that, although it seems simple, it requires great power and becomes increasingly difficult as men age.
During sexual arousal the body generates a natural activator of blood flow the penis called cyclic GMP, which is that which governs the strength of erection in a man during intercourse. After orgasm, cyclic GMP decreases due to an enzyme called phosphoediesterasa-5 (PDE-5) and the erection ends.
What do drugs like Viagra, Cialis and Levitra, is to inhibit PDE-5 to sustain levels of cyclic GMP and get a man to have an erection firmer, more rigid and longer periods during intercourse.
Then analyze each new drugs to know what are the traits that make them different from each other.
Cialis
Recently approved by the European Union, Cialis, born of Eli Lilly and ICOS research firm, becomes a direct competitor to the popular Viagra. Production companies expected to be available in European pharmacies in the first half of next year.
Nicknamed "Le Weekend" (the weekly "), it is said that with one pill taken at dinner on Friday, a man is able to remain sexually potent on Saturday and Sunday. Although it is an exaggerated view that few mortals could well bear, does offer great advantages over Viagra.
· Addition to more prolonged effects, with a single dose are possible multiple sexual episodes.
· Allows achieving a more successful 24 to 36 hours after taking the drug.
· Viagra does not work well when taken with food or after alcohol. Cialis works well with or without food and is effective even after a moderate alcohol intake.
· With Viagra you have to wait at least an hour for sex. Cialis is effective for 15-20 minutes.
· Unlike Viagra, does not cause blue vision.
Cialis also has few side effects. New PDE-5 inhibitors strengthen erections by increasing blood flow to the penis, but also widen the vessels in other parts of the body, resulting in a small percentage of men, headache, nasal congestion and stomach upset. These effects diminish with use.
Levitra
Next year the pharmaceutical market focused on treatments for male impotence, will have another rival: the Levitra (trade name given by Bayer and GlaxoSmithKline for the active ingredient vardenafil).
Medical study performed in 4,000 patients, the results show that Levitra improved erectile function 85% of patients. It is also envisaged that this drug is more effective in men suffering from diabetes, high blood pressure or psychological stress.
In the U.S., Europe and Japan for the marketing authorization and is being processed, while some Latin American countries and the drug has been registered.
Uprima e Ixense
Uprima and Ixense are trade names under which it has submitted a new drug for the treatment of male erectile dysfunction: apomorphine.
Developed by the Japanese pharmaceutical Takeda Chemical Industries in Europe has come under the name of Ixense. In the U.S. market is expected to end 2003 with the name of Uprima.
This new drug is different from Viagra in that it stimulates the brain areas that directly control the sexual functions, is not directed to activate the blood flow.
Apomorphine has the following characteristics:
· Drug sublingual.
· Effective within 20 minutes of administration.
• The effect is exerted at the central nervous system, not in blood vessels.
· Patients with stable angina treated with nitrates apomorphine can be used without problems.
· Foods and alcohol do not affect its absorption.
· If accidentally swallowed it is inactive.
Its side effects are mild. Most common: nausea, headache and dizziness. Often occur early in treatment.
Erectile dysfunction in figures
Erectile dysfunction is a very serious sexual problem that affects 152 million people worldwide. In Europe alone there are 30 million sufferers, of whom 2 million are Spanish. In addition, more than half of men after age 40 suffer or have suffered an episode of impotence. And only 20% of the affected population undergoes medical treatment.
These figures are disturbing. The quality of life we have today, stress, diet and disease make this an increasingly common problem in society. Problem is often suffer in silence in many rooms around the world. But do not be ashamed. Medicines like these may help improve the quality of sexual life of many couples.
